Nozaki Lab

Deaprtment of of Pharmacology & Immunology

Medical University of South Carolina in Charleston, SC

Our Mission

Welcome to Nozaki Lab! We are an immunology Lab in Medical University of South Carolina.

We aim to uncover fundamental mechanisms of intestinal immunity during infection and inflammation, especially by focusing on innate sensor, cell death and its-associated pathways.

Principal Investigator

Kengo Nozaki, MD, Ph.D. is an Assistant Professor of the Department of Pharmacology & Immunology at the Medical University of South Carolina.

Selected Publications

1.     Nozaki K#, Miao EA#. Bucket lists must be completed during cell death. Trends Cell Biol. 2023 Mar 22:S0962-8924(23)00040-5. doi: 10.1016/j.tcb.2023.02.008.

# Corresponding authors

2.     Nozaki K*, Maltez VI*, Rayamajhi M, Tubbs AL, Mitchell JE, Lacey CA, Harvest CK, Li L, Nash WT, Larson HN, McGlaughon BD, Moorman NJ, Brown MG, Whitmire JK, Miao EA. Caspase-7 activates ASM to repair gasdermin and perforin pores. Nature. 2022 Jun;606(7916):960-967. doi: 10.1038/s41586-022-04825-8. Epub 2022 Jun 15.

* These authors contributed equally.

3.     Nozaki K, Li L, Miao EA. Innate Sensors Trigger Regulated Cell Death to Combat Intracellular Infection. Annu. Rev. Immunol. 2022. 2022 Feb 9. doi: 10.1146/annurev-immunol-101320-011235.

4.     Nozaki K, Mochizuki W, Matsumoto Y, Matsumoto T, Fukuda M, Mizutani T, Watanabe M, Nakamura T. Co-culture with Intestinal Epithelial Organoids Allows Efficient Expansion and Motility Analysis of Intraepithelial Lymphocytes. J Gastroenterol. 2016 Mar;51(3):206-13.

Join our team.